2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W296398
    5-Bromo-N,N-dimethyltryptamine
    5-Bromo-N,N-dimethyltryptamine, an active metabolite, is an antidepressant and sedative drug lead. 5-Bromo-N,N-dimethyltryptamine shows strong affinity towards 5-HT1A, 5-HT2B, 5-HT6, and 5-HT7.
    5-Bromo-N,N-dimethyltryptamine
  • HY-136612R
    DCBA (Standard)
    Pteroic acid (Standard) is the analytical standard of Pteroic acid. This product is intended for research and analytical applications. Pteroic acid is an active compound.
    DCBA (Standard)
  • HY-B0602D
    (S)-(+)-O-Desmethyl Venlafaxine
    (S)-(+)-O-Desmethyl Venlafaxine is a S-enantiomer of O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.
    (S)-(+)-O-Desmethyl Venlafaxine
  • HY-W009512R
    CVT-2738 (Standard)
    CVT-2738 (Standard) is the analytical standard of CVT-2738. This product is intended for research and analytical applications. CVT-2738 is an orally active metabolite of Ranolazine (HY-B0280). CVT-2738 has a protective effect against isoprenaline (HY-108353)-induced myocardial ischemia in mice. CVT-2738 can be used in myocardial ischemia research.
    CVT-2738 (Standard)
  • HY-158747
    CBDPA (CRM)
    		Control
    CBDPA (CRM) is a precursor to CBDP, a synthetic plant cannabinoid. CBDPA (CRM) is a standard substance.
    CBDPA (CRM)
  • HY-137188
    Perindopril acyl-β-D-glucuronide
    Perindopril acyl-β-D-glucuronide is a metabolite of Perindopril (HY-B0130). Perindopril is an ACE inhibitor.
    Perindopril acyl-β-D-glucuronide
  • HY-138627AR
    AST5902 trimesylate (Standard)
    AST5902 (trimesylate) (Standard) is the analytical standard of AST5902 (trimesylate). This product is intended for research and analytical applications. AST5902 trimesylate is the principal metabolite of Alflutinib (AST2818) both in vitro and in vivo. AST5902 trimesylate exerts antineoplastic activity. Alflutinib is an EGFR inhibitor[1].
    AST5902 trimesylate (Standard)
  • HY-W777477
    Homovanillic Acid-13C6
    Homovanillic Acid-13C6 (Vanilacetic acid-13C6) is the 13C-labeled Homovanillic acid (HY-N0384). Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
    Homovanillic Acid-<sup>13</sup>C<sub>6</sub>
  • HY-143993S
    Maytansinoid DM4 impurity 3-d6
    Maytansinoid DM4 impurity 3-d6 is the deuterium labeled Maytansinoid DM4 impurity 3.
    Maytansinoid DM4 impurity 3-d<sub>6</sub>
  • HY-131280R
    Devaleryl Valsartan Impurity (Standard)
    L-Aspartyl-L-phenylalanine (Standard) is the analytical standard of L-Aspartyl-L-phenylalanine. This product is intended for research and analytical applications. L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM.
    Devaleryl Valsartan Impurity (Standard)
  • HY-W017434R
    3,4-Dimethylbenzoic acid (Standard)
    3,4-Dimethylbenzoic acid (Standard) is the analytical standard of 3,4-Dimethylbenzoic acid. This product is intended for research and analytical applications. 3,4-Dimethylbenzoic acid acts as a product of dimethylbenzoate metabolism by Rhodococcus rhodochrous N75[1].
    3,4-Dimethylbenzoic acid (Standard)
  • HY-131306
    Δ2-cis-Hexadecenoic acid
    Δ2-cis-Hexadecenoic acid is an unsaturated fatty acid that is a hydrolysate of lipopolysaccharide (HY-D1056).
    Δ2-cis-Hexadecenoic acid
  • HY-119223S
    Desmethylmirtazapine-d6 hydrochloride
    Desmethylmirtazapine-d6 hydrochloride (Normirtazapine-d6 hydrochloride) is the deuterium labeled Desmethylmirtazapine (HY-119223). Desmethylmirtazapine is an active metabolite of Mirtazapine that has antidepressant effects.
    Desmethylmirtazapine-d<sub>6</sub> hydrochloride
  • HY-12753S
    Debutyldronedarone-d7
    		≥98.0%
    Debutyldronedarone-d7 is deuterium labeled Debutyldronedarone. Debutyldronedarone is a major circulating active metabolite of dronedarone (HY-A0016) in humans.Debutyldronedarone exhibits a potency that is 1/10 to 1/3 of that of the parent agent.
    Debutyldronedarone-d<sub>7</sub>
  • HY-W006000R
    Tetrachlorocatechol (Standard)
    Tetrachlorocatechol (Standard) is the analytical standard of Tetrachlorocatechol. This product is intended for research and analytical applications. Tetrachlorocatechol is a metabolite of pentachlorophenol. Tetrachlorocatechol is one of the most toxic chlorinated catechol produced by the chlorobleaching of pulp and frequently found in the kraft pulp mill effluents[1][2].
    Tetrachlorocatechol (Standard)
  • HY-N0384S1
    Homovanillic acid-d2
    Homovanillic acid-d2 (Vanilacetic acid-d2) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
    Homovanillic acid-d<sub>2</sub>
  • HY-133695
    Florfenicol amine
    Florfenicol amine is a metabolite of Florfenicol (HY-B1374). Florfenicol, a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases.
    Florfenicol amine
  • HY-143965S
    Imidacloprid impurity 2-d4 hydrochloride
    Imidacloprid impurity 2-d4 (hydrochloride) is the deuterium labeled Imidacloprid impurity 2-d4 (hydrochloride).
    Imidacloprid impurity 2-d<sub>4</sub> hydrochloride
  • HY-116026R
    3-Hydroxycarbofuran (Standard)
    3-Hydroxycarbofuran (Standard) is the analytical standard of 3-Hydroxycarbofuran. This product is intended for research and analytical applications. 3-Hydroxycarbofuran, a major metabolite of Carbofuran, is a reversible acetylcholinesterase (AChE) inhibitor.
    3-Hydroxycarbofuran (Standard)
  • HY-135325R
    4-Hydroxyacetophenone oxime (Standard)
    Pyrrole-2-carboxaldehyde (Standard) is the analytical standard of Pyrrole-2-carboxaldehyde. This product is intended for research and analytical applications. Pyrrole-2-carboxaldehyde has vibrational and electronic characteristics used to establish the existence of dimeric form in solid phase and monomeric form in solution phase.
    4-Hydroxyacetophenone oxime (Standard)
Cat. No. Product Name / Synonyms Application Reactivity